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Anti epileptic Pharmaceutical Raw Materials Pregabalin 99.9% Purity CAS 148553-50-8

China Anti epileptic Pharmaceutical Raw Materials Pregabalin 99.9% Purity CAS 148553-50-8 supplier

Large Image :  Anti epileptic Pharmaceutical Raw Materials Pregabalin 99.9% Purity CAS 148553-50-8

Product Details:

Place of Origin: China
Brand Name: SR
Certification: ISO9001
Model Number: 148553-50-8

Payment & Shipping Terms:

Minimum Order Quantity: 1g
Price: negotiable
Packaging Details: as your requirements
Delivery Time: 1-2 days
Payment Terms: T/T, Western Union, MoneyGram
Supply Ability: 2000kg/month
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Detailed Product Description
Color: White Appearance: Powder
Cas: 148553-50-8 Purity: 99.9%
Usage: For Lab Research Payment Method: T/T, Western Union, MoneyGram, Bitcoin
Email: Srchemsale@gmail.com Skype: Live:srchemsale

Pregabalin Pharmaceutical Raw Materials Pregabalin 99.9% Purity CAS 148553-50-8 Anti-epileptic Pharmaceutical powder

 

Product Description:

 

Synonym: Pregablin;3-(Aminomethyl)-5-methyl-hexanoic acid
CAS: 148553-50-8
MF: C8H17NO2
MW: 159.23
Assay: 99.5%
Appearance: White Crystal Powder
Payment: T/T, Western Union and Money Gram
Delivery: Within 24hours After Your Payment
Express: EMS, DHL, FedEx, etc(door-to-door)
Usage: New antiepileptic drugs.  Used in the treatment of peripheral neuropathy, or partial seizures adjuvant treatment.


Product introduction:

Pregabalin works by reducing the abnormal electrical activity in the brain. It is taken alongside other medicines for epilepsy. Pregabalin can also be helpful in treating the symptoms of generalised anxiety disorder (GAD), particularly if other medicines which are more often prescribed for people with this condition are not suitable. GAD is a long-term condition where anxiety is a major symptom.

Pregabalin, also known as β-isobutyl-γ-Aminobutyric acid (β-isobutyl-GABA) and sold under the trade name Lyrica among others, is a medication used to in the treatment of epilepsy, neuropathic pain, fibromyalgia and generalized anxiety disorder. Its use for epilepsy is as an add-on therapy for partial seizures with or without secondary generalization in adults.

Pregabalin is a structural analogue of the neurotransmitter GABA, consequently it belongs to the γ-Aminobutyric acid analogue class of antiepileptic drugs. Its a ion channel modulator that has analgesic, anticonvulsant, sedative, and anxiolytic properties. Pregabalin is a potent gabapentinoid and close analogue of GABOB (β-hydroxy-GABA), baclofen (β-(4-chlorophenyl)-GABA), and phenibut (β-phenyl-GABA).


Product Avail:

Pregabalin belongs to a group of medicines known as anti-epileptic medicines, although it is prescribed for the treatment of several different conditions. You may have been prescribed it for the treatment of partial seizures, which is a type of epilepsy. A seizure is a short episode of symptoms which is caused by a burst of abnormal electrical activity in the brain. With a partial seizure, the burst of electrical activity stays in one part of the brain. Therefore, you tend to have localised or 'focal' symptoms. Pregabalin is also prescribed to treat certain types of long-lasting pain caused by damage to nerves. This type of pain, called neuropathic pain, can be caused by a number of different conditions, including diabetes (where it is called diabetic neuropathy) and shingles(where it is called postherpetic neuralgia). Steroid


Medical uses


Seizures


Pregabalin is useful when added to other treatments, when those other treatments are not controling partial epilepsy. Its use alone is less effective than some other seizure medications. It is unclear how it compares to gabapentin for this use.


Neuropathic pain


The European Federation of Neurological Societies recommends pregabalin as a first line agent for the treatment of pain associated with diabetic neuropathy, post-herpetic neuralgia, and central neuropathic pain. A minority obtain substantial benefit, and a larger number obtain moderate benefit. Other first line agents, including gabapentinand tricyclic antidepressants, are given equal weight as first line agents, and unlike pregabalin, are available as less expensive generics.


Pregabalin is not recommended for certain other types of neuropathic pain such as pain that of trigeminal neuralgia or HIV infection and its use in cancer-associated neuropathic pain is controversial.There is no evidence for its use in the prevention of migraines and gabapentin has been found not to be useful. It has been examined for the prevention of post-surgical chronic pain, but its utility for this purpose is controversial.


Pregabalin is generally not regarded as efficacious in the treatment of acute pain. In clinical trials examining the utility of pregabalin for the treatment of acute post-surgical pain, no effect on overall pain levels was observed, but people did required less morphine and had fewer opioid-related side effects.

 

Anxiety disorders


The World Federation of Biological Psychiatry recommends pregabalin as one of several first line agents for the treatment of generalized anxiety disorder, but recommends other agents such asSSRIs as first line treatment for obsessive-compulsive disorder and post-traumatic stress disorder.It appears to have anxiolytic effects similar to benzodiazepines with less risk ofdependence.


Therapeutic effects of pregabalin appear after 1 week of use and is similar in effectiveness to venlafaxine, but pregabalin has demonstrated superiority by producing more consistent therapeutic effects for psychic and somatic anxiety symptoms.Long-term trials have shown continued effectiveness without the development of tolerance, and, in addition, unlike benzodiazepines, it has a beneficial effect on sleep and sleep architecture, characterized by the enhancement of slow-wave sleep. and produces less severe cognitive and psychomotor impairment; it also has a low potential for abuse and dependence and may be preferred over the benzodiazepines for these reasons.

 

Pregabalin belongs to a group of medicines known as anti-epileptic medicines, although it is prescribed for the treatment of several different conditions. You may have been prescribed it for the treatment of partial seizures, which is a type of epilepsy. A seizure is a short episode of symptoms which is caused by a burst of abnormal electrical activity in the brain. With a partial seizure, the burst of electrical activity stays in one part of the brain. Therefore, you tend to have localised or 'focal' symptoms.


Pregabalin is also prescribed to treat certain types of long-lasting pain caused by damage to nerves. This type of pain, called neuropathic pain, can be caused by a number of different conditions, including diabetes (where it is called diabetic neuropathy) and shingles(where it is called postherpetic neuralgia).


How to use Pregabalin


LYRICA (pregabalin) oral solution, 20 mg/mL, is administered orally and is supplied as a clear, colorless solution contained in a 16 fluid ounce white HDPE bottle with a polyethylene-lined closure. The oral solution contains 20 mg/mL of pregabalin, along with methylparaben, propylparaben, monobasic sodium phosphate anhydrous, dibasic sodium phosphate anhydrous, sucralose, artificial strawberry #11545 and purified water as inactive ingredients.


How often do take Pregabalin?


Take this medication by mouth usually twice or three times a day with or without food.
Use this medication regularly in order to get the most benefit from it.
Remember to use it at the same time each day - unless specifically told not to by your doctor.
It may take some time before the full benefit of this drug takes effect.
Certain medical conditions may require different dosage instructions as directed by your doctor.

Pregabalin dose

Dosage is based on your age, gender, medical condition, response to therapy, and use of certain interacting medicines.

Pregabalin Using Notes


Pregabalin may produce dizziness, sleepiness and decreased concentration. You should not drive, operate complex machinery or engage in other potentially hazardous activities until you know whether this medication affects your ability to perform these activities. Consult your doctor or pharmacist for more details.

 

Product Name: Pregabalin
MF: C8H17NO2
MW: 159.23
Assay: 99.9%
Appearance: White Crystal Powder
Usage: New antiepileptic drugs. Used in the treatment of peripheral neuropathy, or partial seizures

Pregabalin is described chemically as (S)-3-(aminomethyl)-5-methylhexanoic acid. The molecular formula is C8H17NO2 and the molecular weight is 159.23.

Pregabalin is a white to off-white, crystalline solid with a pKa1 of 4.2 and a pKa2 of 10.6. It is freely soluble in water and both basic and acidic aqueous solutions. The log of the partition coefficient (n-octanol/0.05M phosphate buffer) at pH 7.4 is 1.35.

LYRICA (pregabalin) Capsules are administered orally and are supplied as imprinted hard-shell capsules containing 25, 50, 75, 100, 150, 200, 225, and 300 mg of pregabalin, along with lactose monohydrate, cornstarch, and talc as inactive ingredients. The capsule shells contain gelatin and titanium dioxide. In addition, the orange capsule shells contain red iron oxide and the white capsule shells contain sodium lauryl sulfate and colloidal silicon dioxide. Colloidal silicon dioxide is a manufacturing aid that may or may not be present in the capsule shells. The imprinting ink contains shellac, black iron oxide, propylene glycol, and potassium hydroxide.

LYRICA (pregabalin) oral solution, 20 mg/mL, is administered orally and is supplied as a clear, colorless solution contained in a 16 fluid ounce white HDPE bottle with a polyethylene-lined closure. The oral solution contains 20 mg/mL of pregabalin, along with methylparaben, propylparaben, monobasic sodium phosphate anhydrous, dibasic sodium phosphate anhydrous, sucralose, artificial strawberry #11545 and purified water as inactive ingredients.

 

 

 

Company Introduction:

Shandong Shengri Chemical Co., Ltd.

Shandong Shengri Chemical Co., Ltd. is located in Shandong province, China.

Shandong Shengri Chemical Co., Ltd. is an experienced enterprise of manufacturing various kind of research chemicals(cannabinoids and stimulant), steroids, Human Growth Hormone HGH, hyaluronic acid and peptide products.
Shandong Shengri Chemical Co., Ltd. research and development center also offers custom synthesis services.

 

Price, Company and Service Advantage:

1 Best service, high quality and reasonable price

2. It's customers' right to choose the package (EMS, DHL, FedEx, UPS);

3. It's customers' right to choose the packing way for his produccts from many recent effective packing ways

4. Specials are possible when client's order is big enough, including the discount policy;

5. Our company promise to deliver clients' package to his hands safely, or we'll cover the total loss and reship your order;

6. Return policy: we promise we will return your money if our product don't have effect


Our Advantages:

1.we have over 10 years experience in this aera

2.we can provide competitive price for every customer and guarantee the quality of our goods.

3.we are attention to every customer's requirements and make a good relationship with them.

4.we have a long business relationship with many countries, such as canada, mexico, brazil, united kingdom, russia, germany, india, south africa, malta, egypt, armenia, australia, philippines, belgium, netherlands, denmark ect.

If you have any other questions to consult me.please not hesitate to contact me at any time.

 

1. Why Choose Us

1. rich experience
we specialize in this filed for many years,our steriods and hormones exported to all over the world and established long friendly relations of coroperation with them.

2. great quality,purity and favorable
good quality is one of our biggest secert to success;u can get the best quality and service from us.

3. safest and fastest delivery
we have adequate stock so that we can deliver the products with 24 hours as soon as receiving the payment.fast and discreet shipment will be arranged to pass customs.

4. good package
unique ways to ship 10g to 100kg powders to your destination.we offer melting powder into liquid service and ship the liquid in special bottles.

5. great after-sales service
any questions or problems after receiving the product,pls feel free to contact us.problems would be solved immediately.

 

2. Order Guide

Q1: have your product quality been approved by third party lab
A: yes, all products are strictly tested by our qc, confirmed by qa and approved by third party lab in china, usa, canada, germany, uk, italy, france etc. so you will be assured with good quality if you choose us.

Q2: how do you treat quality complaint
A: first of all, our qc department will do strict examination of our export products by hplc, uv, gc , tlc and so on in order to reduce the quality problem to near zero. if there is a real quality problem ,caused by us, we will send you free goods for replacement or refund your loss.

Q3: is there any discount
A: yes, for larger quantity, we always support with better price.

Q4: how long does it take to the goods arrived
A:it is depending on your location,
for small order, please expect 5-7 days by dhl,ups,tnt, fedex, ems.
for mass order, please allow 5-8 days by air, 20-35 days by sea.

Q5 do you have any reshipment policy
A: we have good after-sale service and re-shipment policy if the parcel lose.

 

Contact:

Email: srchemsale@gmail.com
Skype: live:srchemsale

 

Anti epileptic Pharmaceutical Raw Materials Pregabalin 99.9% Purity CAS 148553-50-8

 

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